Bisphosphonate Drug Holiday and Fracture Risk
نویسندگان
چکیده
منابع مشابه
Evaluation of fracture risk and potential drug holidays for postmenopausal women on long-term bisphosphonate therapy
STUDY OBJECTIVE To describe characteristics of postmenopausal women on long-term bisphosphonate therapy who fall into one of four fracture risk categories (low, mild, moderate, high), and to determine the prevalence of women eligible for a drug holiday. DESIGN Retrospective electronic health record review. SETTING Eight primary care clinics within a university-based health care system. PA...
متن کاملEffects of a 'Drug Holiday' on Bone Mineral Density and Bone Turnover Marker During Bisphosphonate Therapy
BACKGROUND Recently long-term safety of bisphosphonate raises issues about the duration of therapy. We examined the effects of a drug holiday (DH) on bone mineral density (BMD) and bone turnover markers. METHODS In Korean, 125 women of 50 years of age or older with T-score≤-3.0 of their lumbar or left femoral BMD initiated bisphosphonate from 1999 based on retrospective chart review. 125 pati...
متن کاملBisphosphonate-associated atypical fracture of the femur: Spontaneous healing with drug holiday and re-appearance after resumed drug therapy with bilateral simultaneous displaced fractures — a case report
Open Access This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the source is credited. DOI 10.3109/17453674.2011.581267 Our patient is a 64-year-old Chinese woman with a history of asthma with previous prednisolone usage, diabetes mellitus, and breast ca...
متن کاملRisk of atypical femoral fracture during and after bisphosphonate use
BACKGROUND AND PURPOSE Use of bisphosphonates in women is associated with higher risk of atypical femoral fractures. The risk in terms of timing of use and type of bisphosphonate, and in men, remains unclear. PATIENTS AND METHODS We reviewed radiographs of 5,342 Swedish women and men aged 55 years or more who had had a fracture of the femoral shaft in the 3-year period 2008-2010 (97% of those...
متن کاملIncrease in the Serum Parathyroid Hormone Level During a Bisphosphonate Drug Holiday
After discontinuation of bisphosphonate therapy, an antiresorptive effect and antifracture protection persist for an undefined period. Patients are encouraged to continue calcium and vitamin D supplementation, during a bisphosphonate drug holiday. However, assessment of adequate calcium intake during the bisphosphonate drug holiday is difficult. Therefore, we measured the serum intact parathyro...
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ژورنال
عنوان ژورنال: Journal of Patient-Centered Research and Reviews
سال: 2015
ISSN: 2330-0698
DOI: 10.17294/2330-0698.1106